What is TGF beta-1?
TGF beta stimulates EGF receptors Decreased levels of glutathione will stimulate production of TGF-β, and when glutathione is replenished, the production of TGF-β will be decreased. Results of high TGF beta-1 With high levels of TGF beta-1 you see lung symptoms, neurological problems, learning disability, resting tremors, unusual seizures.
What is T-regulatory CD4+CD25++ and TGF beta 1?
Mucous membranes line various cavities in the body and surround internal organs. Quest can test for T-regulatory CD4+CD25++ and CD4+CD25++127lo/- cells. High levels of TGF beta 1 damages the lungs by causing the soft bronchial tube lining in lungs to become thick and stiff (fibroblasts/fibrosis) that then makes it more difficult to breathe.
What happens if there is no TGF beta 1 in mice?
In mice if they have no TGF beta-1 it induces autoimmune disease. The common autoantibody production most commonly seen with CIRS involves antigliadin antibodies of the IgG class and anticardiolipins of the IgM class. There are other autoantibodies made that react to gliadin and cardiolipin.
What happens if TGF beta 1 is too high?
High levels of TGF beta 1 damages the lungs by causing the soft bronchial tube lining in lungs to become thick and stiff (fibroblasts/fibrosis) that then makes it more difficult to breathe. Lung remodeling can lead to asthma like symptoms.