What is ht29 cell line?
HT-29 is a human colorectal adenocarcinoma cell line with epithelial morphology. These cells are sensitive to the chemotherapeutic drugs 5-fluorouracil and oxaliplatin, which are standard treatment options for colorectal cancer.
What is SW620 cell line?
SW620 [SW-620] cells are isolated from the large intestine of a 51-year-old male Dukes C colorectal cancer patient. The cells can be used for cancer and toxicology research and high-throughput screening. Homo sapiens, human. Morphology epithelial Tissue Large intestine; Colon Disease.
What is A2780 cell line?
Cell Line Description The A2780 human ovarian cancer cell line was established from tumour tissue from an untreated patient. Cells grow as a monolayer and in suspension in spinner cultures. A2780 is the parent line to the cisplatin resistant cell line A2780 cis (Sigma catalogue no.
What is the difference between a cell and cell line?
Primary cell culture is the culture of cells directly isolated from parental tissue of interest; whereas cell line is the culture of cells originated from a primary cell culture, which is generally used to expand cell population and prolong life span. However, cell lines have prolonged lifespan.
What is cell line and its types?
Attached cell lines can be classified as 1) endothelial such as BAE-1, 2) epithelial such as HeLa, 3) neuronal such as SH-SY5Y, or 4) fibroblast such as MRC-5. Figure 1. Cells are classified in 4 different cell type categories based on overall morphology 1) Epithelial 2) Endothelial 3) Neuronal or 4) Fibroblast.
What is OVCAR3?
NIH:OVCAR-3 [OVCAR3] are epithelial cells that were isolated in 1982 from the malignant ascites of a patient with progressive adenocarcinoma of the ovary. Use these cells to study drug resistance in ovarian cancer.
Is SKOV3 a Hgsoc?
However, a recent analysis of ovarian cancer cell lines in the Cancer Cell Line Encyclopedia (CCLE) indicated that the most commonly used cellular models of HGSOC (i.e., SKOV3 and A2780) do not mimic the genomic characteristics of tumors in The Cancer Genome Atlas (TCGA) database and suggested that future research …
What is HT-29 cell line?
HT-29 is sensitive to the chemotherapeutic drugs 5-fluorouracil and oxaliplatin, which is a standard treatment option for colorectal cancer. In addition to being a xenograft tumor model for colorectal cancer, the HT-29 cell line is also used as an in vitro model to study absorption, transport, and secretion by intestinal cells.
Is HT29 an adenocarcinoma?
Keywords HT29 • Cell differentiation • Transport studies • Intestinal cell The human colon adenocarcinoma cell line HT29 was isolated from a primary tumor of a 44 years old Caucasian female in 1964 by Fogh and Trempe (1975). Since then, many cell lines have been derived from human colon cancers.
What is WIDR (HT-29)?
Chen TR, et al. WiDr is a derivative of another colon adenocarcinoma cell line, HT-29. Cancer Genet. Cytogenet. 27: 125-134, 1987. PubMed: 3472642 Fogh J, et al. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J.
What is the difference between Caco-2 and HT-29 cells?
The HT-29 cell line has also been used in Giardia interaction studies, and it is more heterogeneous than the Caco-2 cell line, consisting mainly of un-differentiated cells and a smaller mucus producing subpopulation (3–5%) ( Huet et al., 1987; Maoret et al., 1989 ).