What is Elastolytic granuloma?
Annular elastolytic giant cell granuloma (AEGCG), is a rare granulomatous disorder characterized by annular plaques with elevated borders and central atrophy with a tendency to occur over sun exposed areas, rarely involving covered areas.
Is central giant cell granuloma a tumor?
Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity.
What are giant cells granulomas?
Giant cell granuloma is a benign reactive osseous proliferation that shares many features with aneurysmal bone cyst; in many regards, these lesions are indistinguishable. 124. In the head and neck area, the most common sites of occurrence are the maxilla and mandible.
What causes central giant cell granuloma?
Central giant cell granuloma is a fairly common lesion in the jaws aetiology of which is still completely unknown but thought to be of a reactive process to some unknown stimuli. It usually arises either peripherally in periodontal ligament, mucoperiosteum, or centrally in the bone.
What is granuloma?
A granuloma is a small area of inflammation. Granulomas are often found incidentally on an X-ray or other imaging test done for a different reason. Typically, granulomas are noncancerous (benign). Granulomas frequently occur in the lungs, but can occur in other parts of the body and head as well.
What is a granuloma on the skin?
Granuloma annulare is a benign skin condition characterized by small, raised bumps that form a ring with a normal or sunken center. The cause of granuloma annulare is unknown and it is found in patients of all ages. The condition tends to be seen in otherwise healthy people.
How common is central giant cell granuloma?
Background: Giant cell granuloma (GCG) is an uncommon, benign, proliferative, intraosseous lesion representing < 7% of all benign jaw lesions.
How do you treat central giant cell granulomas?
Treatment options advocated vary from case to case depending on the clinical characteristics and behavior and range from surgical excision or resection with continuity defect, cryotherapy, to enucleation and aggressive local curettage with or without chemical cauterization.
How are giant cell granulomas treated?
Treatment:
- There have been reports of central GCGs resolving spontaneously; however, treatment is often required.
- The typical small, slow-growing lesions can be treated with nonsurgical methods, including radiotherapy, daily calcitonin injections, intralesional corticosteroid injections, and interferon alpha.
Is giant cell granuloma painful?
Perioral and intraoral characteristics: The CGCG are usually painless unless the size and expansion of the lesion becomes excessive. Found primarily anterior to the first molar, radiographic appearances may be noted because of the divergence and expanding margins of a radiolucent lesion.
Is granuloma a tumor?
A granuloma is a tiny cluster of white blood cells and other tissue that can be found in the lungs, head, skin or other parts of the body in some people. Granulomas are not cancerous. They form as a reaction to infections, inflammation, irritants or foreign objects.
How serious is granuloma?
People with chronic granulomatous disease experience serious bacterial or fungal infection every few years. An infection in the lungs, including pneumonia, is common. People with CGD may develop a serious type of fungal pneumonia after being exposed to dead leaves, mulch or hay.