What class of drug is doxorubicin?

What class of drug is doxorubicin?

Doxorubicin is in a class of medications called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.

What is the drug action of doxorubicin?

Doxorubicin is a type of chemotherapy drug called an anthracycline. It slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2. Cancer cells need this enzyme to divide and grow. You might have doxorubicin in combination with other chemotherapy drugs.

What are the properties of doxorubicin?

Doxorubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II.

Is doxorubicin an antibiotic?

Doxorubicin is an antibiotic derived from the Streptomyces peucetius bacterium. It has widespread use as a chemotherapeutic agent since the 1960s. Doxorubicin is part of the anthracycline group of chemotherapeutic agents.

How do you feel after doxorubicin?

The following side effects are common (occurring in greater than 30%) for patients taking Doxorubicin:

1. Pain along the site where the medication was given.
2. Nausea or vomiting (You will be pretreated for this side effect)Later Side Effects: (within two weeks after treatment begins)

What is the most common side effect of doxorubicin?

Commonly reported side effects of doxorubicin include: severe nausea and vomiting, nausea and vomiting, and alopecia.

Which is the most serious side effect of doxorubicin?

This medicine may cause irreversible heart muscle damage, leading to heart failure. This is more likely to occur if you have other heart problems, have had or currently receiving radiation therapy to your chest, or have received other cancer medicines.

How long does doxorubicin take to work?

Liposomal doxorubicin is a light red liquid that you have through a drip (infusion) into your bloodstream. It usually takes between 30 to 90 minutes each time you have it.

Why is doxorubicin called Red death?

Additionally, some people may develop PPE, characterized by skin eruptions on the palms of the hand or soles of the feet, swelling, pain, and erythema. Due to these side effects and its red color, doxorubicin has earned the nickname “red devil” or “red death.”

When do doxorubicin side effects start?

Nausea or vomiting (You will be pretreated for this side effect)Later Side Effects: (within two weeks after treatment begins)

Who should not take doxorubicin?

Bone marrow problem (eg, drug-induced myelosuppression), severe or. Heart attack, recent (within 4 to 6 weeks) or. Heart disease, severe or. Liver disease, severe—Should not be used in patients with these conditions.

How does Adriamycin make you feel?

SIDE EFFECTS: Nausea, vomiting, diarrhea, and loss of appetite may occur. Nausea and vomiting can be severe. In some cases, drug therapy may be needed to prevent or relieve nausea and vomiting. Not eating before your treatment may help relieve vomiting.