Is mithramycin is antibiotic?
Mithramycin, otherwise known as plicamycin, is an antibiotic agent that was initially used to treat testicular neoplasms and was found to lower serum calcium levels.
What does actinomycin D do?
Actinomycin D is a well-known antibiotic of the actinomycin group that exhibits high antibacterial and antitumor activity. Actinomycin D has been widely used in clinical practice since 1954 as an anticancer drug for treating many tumors and it is also a useful tool in biochemistry and molecular biology.
What is pamidronate dog?
Pamidronate is one of the most commonly used bisphosphonates in veterinary medicine. This medication is given as an intravenous infusion, meaning it is mixed in a large volume of fluid and given over several hours through a vein. When used to palliate bone tumor pain such infusions are given every 3-6 weeks.
Can you overdose on azithromycin?
In case of overdose If you take too much azithromycin, you could have dangerous levels of the drug in your body. This may cause liver damage and irregular heart rhythm. If you think you’ve taken too much of this drug, call your doctor or local poison control center.
How is azithromycin overdose treated?
If you take too much azithromycin, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
Is ivermectin toxic to dogs?
Toxicity to pets A class of drugs commonly used in veterinary medicine include ivermectin, milbemycin, and moxidectin; these are anthelmintics (these drugs kill parasites) and are commonly used as an active ingredient for monthly heartworm preventatives.
What are the side effects of Mithracin (Plicamycin)?
The most common side effects reported with the use of Mithracin (plicamycin) consist of gastrointestinal symptoms: anorexia, nausea, vomiting, diarrhea, and stomatitis. Other less frequently reported side effects include fever, drowsiness, weakness, lethargy, malaise, headache, depression, phlebitis, facial flushing, and skin rash.
What is the mechanism of action of Plicamycin?
Plicamycin (mithramycin) is an antineoplastic antibiotic that complexes with DNA in the presence of divalent cations such as magnesium. Plicamycin is an antineoplastic antibiotic that complexes with DNA in the presence of divalent cations such as magnesium.
Can Mithracin (Plicamycin) be used for testicular cancer?
Mithracin (plicamycin) may be useful in the treatment of patients with testicular tumors which are resistant to other chemotherapeutic agents. Prior radiation therapy or prior chemotherapy did not alter the response rate with Mithracin (plicamycin) .