Is denatonium benzoate toxic to humans?
When ingested at 10 ppm by human beings, denatonium benzoate has an extremely bitter, unpleasant taste. The addition of denatonium benzoate to liquid dish detergents and orange juice reduces the amount ingested by children. The toxicity of denatonium benzoate is low with acute po LD50’s in rats of 485-740 mg/kg.
Is denatonium benzoate toxic to birds?
Denatonium benzoate is moderately toxic to mammals and has a high tendency to bioaccumulate. It is also an irritant. It is moderately toxic to birds but less so to fish and aquatic invertebrates.
What is Bitrex made of?
Denatonium, usually available as denatonium benzoate (under trade names such as Denatrol, BITTERANT-b, BITTER+PLUS, Bitrex, and Aversion) and as denatonium saccharide (BITTERANT-s), is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharide.
Is denatonium benzoate natural?
There are, in fact, several such substances, both natural and man-made, but one that stands out above all others is denatonium benzoate, or Bitrex, as it is commonly known.
What are the side effects of denatonium benzoate?
Adverse reactions related to denatonium benzoate are rare. A previous report revealed a case with a severe allergic reaction, including urticaria and asthma, resulting from exposure to denatonium benzoate.
What is denatonium benzoate rat poison?
Present day rodent management technology mostly relies on use of rodenticides, which is unsafe for human beings and other non-targets. Denatonium benzoate (DB) is an intensely bitter and non-toxic substance which is detectable by humans at a concentration of 10 ppb.
Where is denatonium benzoate found?
Denatonium Benzoate is a bittering agent which is used to give a bitter taste to toxic products in order to make the product more difficult to ingest. Examples of products which contain denatonium benzoate are: antifreeze, detergents, floor cleaner, paint stripper and toilet cleaner.
Can you be allergic to denatonium benzoate?
How do you neutralize denatonium benzoate?
Bitrex is the most bitter chemical compound and has to be removed before alcohol consumption. The home-made methods utilize sodium hypochlorite to disintegrate particles of denatonium benzoate in alcohol and to remove bitter taste before trading.
What products contain denatonium benzoate?
Is denatonium benzoate safe to use?
The efficacy and safety studies on denatonium benzoate are limited and may be subject to varying interpretations when viewed in the context of a potential poisoning situation. Safety data indicate a low toxicity profile.
What does denatonium benzoate taste like?
When ingested at 10 ppm by human beings, denatonium benzoate has an extremely bitter, unpleasant taste. The addition of denatonium benzoate to liquid dish detergents and orange juice reduces the amount ingested by children. The toxicity of denatonium benzoate is low with acute po LD50’s in rats of 485-740 mg/kg.
What causes hypersensitivity to denatonium benzoate?
He had previously developed the same symptoms following exposure to an alcohol-based skin disinfectant and other products denatured with denatonium benzoate. The cause of his symptoms was thus likely to be an immunologic mechanism of the immediate hypersensitivity-type.
What is the molecular weight of denatonium benzoate?
Denatonium benzoate PubChem CID 19518 Molecular Weight 446.6 Parent Compound CID 15488 (Denatonium) Component Compounds CID 15488 (Denatonium) CID 243 (Benzoic Date s Modify 2021-07-03 Create 2005-08-08