How often do you take melphalan?
In this case, you take melphalan tablets for the first 4 days of each cycle of treatment. A cycle usually lasts 35 days (5 weeks). You usually have up to 8 cycles. Some people might have high doses of melphalan with a stem cell transplant.
How long after melphalan Will my hair fall out?
You may have some thinning of your hair but it is unlikely that you will lose it completely. Thinning or loss of your hair will usually start within two to four weeks of your first dose of melphalan. You may also have thinning or loss of eyelashes, eyebrows and other body hair.
How long does it take to recover from melphalan?
The re-infusion of stem cells takes no more than a few hours and is given through the vein much like a blood transfusion. Depending upon the type, recovery can take 2 to 4 weeks in the hospital and several months or more as an outpatient.
How long before hair grows back after stem cell transplant?
Hair usually starts to grow back about 3 months after the transplant. It’s possible that your hair may grow back with a different texture.
Does melphalan cause diarrhea?
Melphalan when used in high doses for treatment for multiple myeloma can lead to severe mucositis[1,2]. Patient can develop gastrointestinal ulcers, vomiting and diarrhea with the use of high dose melphalan as a conditioning regimen for autologous transplant for multiple myeloma[3-5].
What are melphalan tablets?
MELPHALAN are white to off-white film-coated, round, biconvex tablets engraved “GX EH3” on one side and “A” on the other. Melphalan Tablets are indicated in the treatment of multiple myeloma and advanced ovarian adenocarcinoma.
Does melphalan cause anaphylaxis?
Melphalan. Hypersensitivity reactions, including anaphylaxis, have occurred in approximately 2% of patients who received the IV formulation. Melphalan is leukemogenic in humans. Melphalan produces chromosomal aberrations in vitro and in vivo and, therefore, should be considered potentially mutagenic in humans.
What is 4].melphalan?
Melphalan is a bifunctional alkylating agent which is active against selective human neoplasticdiseases. It is known chemically as 4-[bis(2-chloroethyl)amino]-L-phenylalanine.
How do you dilute melphalan 5 mg?
This provides a 5-mg/mL solution of Melphalan. Rapid addition of the diluent followed by immediate vigorous shaking is important for proper dissolution. Immediately dilute the dose to be administered in 0.9% Sodium Chloride Injection, USP, to a concentration not greater than 0.45 mg/mL.