Does topiramate help OCD?
Conclusion: The results of our study demonstrated that topiramate may augment the therapeutic effect of SSRIs in treatment-resistant OCD patients. However, it should be noted that our study is preliminary and larger double-blind studies are needed to confirm these results.
What is the best drug of choice for treating obsessive-compulsive disorder?
Most commonly, antidepressants are tried first. Antidepressants approved by the U.S. Food and Drug Administration (FDA) to treat OCD include: Clomipramine (Anafranil) for adults and children 10 years and older. Fluoxetine (Prozac) for adults and children 7 years and older.
What is the best treatment for compulsive behavior?
The most effective treatments for OCD are Cognitive Behavior Therapy (CBT) and/or medication.
Can Topamax cause OCD?
One case of OCD associated with topiramate has been reported in a 19-year-old patient, an age that is also consistent with an idiopathic OCD. The OCD improved partially after topiramate discontinuation and the prescription of citalopram.
What is first line treatment for obsessive-compulsive disorder?
Treatment is rarely curative, but patients can have significant improvement in symptoms. Recommended first-line therapy is cognitive behavior therapy with exposure and response prevention or a selective serotonin reuptake inhibitor.
What are the long-term side effects of topiramate?
Long-term side effects of Topamax Most Topamax side effects aren’t permanent, and go away with time. For example, fatigue (low energy) and feelings of burning or numbness in your hands and feet may go away as you continue taking Topamax.
What are the possible side effects of topiramate?
The most common of the side effects was paresthesia (12 cases in topiramate group and 3 in placebo group; P= 0.041) and followed by difficulty with concentration (8 in topiramate group and 2 in placebo group; P= 304). Other adverse effects were included pruritus, insomnia and dizziness (less than 2 cases).
How effective is topiramate 192 mg/day for weight loss?
In a study conducted by Wilding et al., the mean decrease in body weight with topiramate 192 mg/day was 9.1% and 61% of these subjects lost at least 5% of their baseline body weight at week 60 of the treatment. Hence, there were no statistically significant differences in weight loss between the groups treated with doses of 256 and 192 mg/day.[16]
Can aripiprazole and topiramate be used to treat borderline personality disorder?
Co-administration of aripiprazole and topiramate could be a safe and effective long-term treatment for improving not only the symptoms of borderline personality disorder but also the associated health-related quality of life and interpersonal problems. Introduction
Does topiramate improve glycemic control in type 2 diabetes?
In different studies, it has been demonstrated that a modest reduction in body weight will considerably improve glycemic control in subjects with type 2 diabetes.[3] In our study, weight changes from baseline (>5%) were seen in 25% of subjects in the topiramate group compared with the placebo group (<5% of cases).