What is Monckeberg sclerosis?
Monckeberg’s sclerosis is a disease of unknown aetiology characterised by calcification of the media of small-sized and medium-sized arteries1 first described by Johann Georg Monckeberg in 19032 for whom it is eponymously named. The result is progressive stiffening of the elastic layer of the arterial wall.
What is Monckeberg medial calcification?
Monckeberg medial calcific sclerosis (MCS) is a ring-like calcification of the vascular media of small to medium sized vessels without associated intimal thickening. Almost exclusively, MCS is the underlying condition in what is referred to as breast arterial calcification (BAC) detected at mammography.
How do you pronounce Monckeberg?
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What causes hyperplastic arteriosclerosis?
Hyperplastic arteriolosclerosis These changes are most prominent in the kidney and can lead to ischemia and acute kidney failure. It can be caused by malignant hypertension.
What is Calciphylaxis disease?
Calciphylaxis (kal-sih-fuh-LAK-sis) is a serious, uncommon disease in which calcium accumulates in small blood vessels of the fat and skin tissues. Calciphylaxis causes blood clots, painful skin ulcers and may cause serious infections that can lead to death.
What is Monckeberg disease?
What is Monckeberg disease? Monckeberg disease is a condition in which the tunica media, the middle layer of the blood vessel wall, becomes hardened or calcified. This happens through a mechanism entirely different from that of atherosclerosis (hardening due to fatty deposits).
What is Mönckeberg medial calcific sclerosis?
Mönckeberg medial calcific sclerosis is characterised by calcific deposits within the media of medium and small muscular arteries that do not cause luminal narrowing. The calcification is typically diffuse and circumferential along the vessel and is readily visible on plain film.
What is the Mönckeberg model of arteriosclerosis?
Calcium deposition in the media of arteries. (Moenckeberg), Johann G., German pathologist, 1877-1925. Mönckeberg arteriosclerosis – involves the peripheral arteries with deposition of calcium in the medial coat but with little or no encroachment on the lumen.
What is the pathophysiology of Mönckeberg sclerosis of the breast?
Vascular calcification in the breast on mammography is of this type. The exact pathogenesis of Mönckeberg sclerosis is unknown, but it is more common with advancing age, diabetes and chronic renal disease.