What is the difference between DSEK and DMEK?

What is the difference between DSEK and DMEK?

Both DMEK and DSAEK remove Descemet’s membrane and endothelium. DMEK adds only a new Descemet’s membrane and endothelium. DSAEK also adds a new Descemet’s membrane and endothelium but with a layer of donor stroma.

How successful is DMEK surgery?

DMEK surgery is highly successful. If the graft is not fully attached, a small in-office procedure may be needed to place an additional air bubble in the eye. Significant, sight-threatening complications are exceedingly rare.

How is DSEK performed?

With a DSEK procedure only the abnormal inner lining of the cornea is removed. A thin, circular disc is then removed from the inner lining of a donor cornea. This is folded and place inside of the eye where an air bubble pushes it in place until it heals in an appropriate position.

How thick is a DMEK graft?

DMEK is a partial-thickness cornea transplant procedure that involves selective removal of the patient’s Descemet membrane and endothelium, followed by transplantation of donor corneal endothelium and Descemet membrane without additional stromal tissue from the donor. The graft tissue is merely 10-15 microns thick.

What is Descemet stripping endothelial keratoplasty?

In Descemet’s stripping endothelial keratoplasty (DSEK), the patient’s Descemet membrane is peeled off, using specially designed strippers and replaced with a partial thickness graft: a transplanted disc of Posterior Stroma, Descemet and Endothelium (10-30 % of the inner donor cornea).

How long does air bubble last after DMEK?

The air bubble will typically disappear completely 5-7 days after surgery. If you have had a vitrectomy in the past there can also be air that travels to the back of the eye and you may then see two bubbles. This will also disappear.

Is DMEK surgery painful?

Patients undering DMEK surgery receive sedation and anesthesia so there is no pain throughout the procedure. During the surgery, a special gas bubble is placed into the eye to allow the DMEK tissue to properly attach to the patient’s inner cornea.

What is DSEK surgery?

Who invented DSEK?

DSEK/DSAEK/DMEK Endothelial keratoplasty (EK) was introduced by Melles et al. in 1998. Today there are three forms of EK: Deep Lamellar Endothelial Keratoplasty (DLEK) in which the posterior part of the recipient cornea is replaced by donor tissue.

How long does DMEK last?

DMEK and DSAEK are both advanced surgeries for Fuchs’ dystrophy and other causes of corneal endothelial failure, during which a very thin layer of new cells is placed inside the eye. The new cell layer is held in place by an air/gas bubble that supports the new layer and gradually disappears over 3-5 days.

Where is Descemet’s membrane?

Descemet’s membrane— which is the basement membrane for the corneal endothelium— is a dense, thick, relatively transparent and cell-free matrix that separates the posterior corneal stroma from the underlying endothelium.

What is endothelial keratoplasty?

Read our disclaimer for details. Endothelial keratoplasty is a cornea-sparing transplant technique that replaces only the diseased endothelial cell layer of the patient’s cornea. This technique offers many advantages compared with traditional full-thickness cornea transplants.

Is Ek (endothelial keratoplasty) safe and efficacious?

The established procedure, penetrating keratoplasty (PKP), has been used for many years and its safety and efficacy are well known. Endothelial keratoplasty (EK) techniques are relatively new surgical procedures and their safety and efficacy relative to PKP are uncertain.

Is endothelial keratoplasty better for Fuchs endothelial dystrophy?

Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy The rapid growth of endothelial keratoplasty as the treatment of choice for FED is based upon the belief that visual recovery is more rapid, surgically induced astigmatism (regular and irregular) is less and rates of transplant rejection are lower with EK.

Is endothelial keratoplasty the treatment of choice for focal erectile dysfunction (fed)?

The rapid growth of endothelial keratoplasty as the treatment of choice for FED is based upon the belief that visual recovery is more rapid, surgically induced astigmatism (regular and irregular) is less and rates of transplant rejection are lower with EK. This change in practice also assumes that t …